Ditch Traditional Wireframes
Wireframes have played an increasingly leading role in the modern Web development process. They provide a simple way of validating user interface and layout and are cheaper and faster to produce than a final visual comp. However, most of the methods and techniques used to create them are far from being efficient, contradicting the principles and values that made wireframing useful in first place.
“By getting rid of traditional wireframes and directing those efforts toward producing quick mockups first and actual HTML/CSS code later, your design process will account for the limitations and possibilities of the Web (desktop and mobile).”
A great article written by Sergio Nouvel about improving and questioning the deliverables of wireframes.